AN ADJUVANT FORMULATION CONTAINING TOLL-LIKE RECEPTOR 7 AGONIST STIMULATES PROTECTION AGAINST MORBIDITY AND MORTALITY DUE TO ANAPLASMA MARGINALE IN A HIGHLY ENDEMIC REGION OF WEST AFRICA.

An adjuvant formulation containing Toll-like Receptor 7 agonist stimulates protection against morbidity and mortality due to Anaplasma marginale in a highly endemic region of west Africa.

Efficient cattle production and provision of animal-sourced foods in much of Africa is constrained by vector-borne bacterial and protozoal diseases.Effective vaccines are not currently available for most of these infections resulting in a continuous disease burden that limits genetic improvement.We tested whether stimulation of innate immunity usin

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Synthetic virus-like particles target dendritic cell lipid rafts for rapid endocytosis primarily but not exclusively by macropinocytosis.

COLLAGEN POMEGRANATE DC employ several endocytic routes for processing antigens, driving forward adaptive immunity.Recent advances in synthetic biology have created small (20-30 nm) virus-like particles based on lipopeptides containing a virus-derived coiled coil sequence coupled to synthetic B- and T-cell epitope mimetics.These self-assembling SVL

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Implementing a Peer Advocate Mental Health Digital Intervention Program for Ohio Youth: Descriptive Pilot Study

BackgroundIn the United States, millions of adolescents report poor mental health, where 1 in 5 teenagers considers suicide.Reducing stigma and fostering peer support remains critical for positive mental health interventions and programs.Increasingly, digital mental health tools have emerged with great promise, leveraging social networks.Despite th

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